ZIP Codes of Florence County, SC

Population & People
Population & People
Total Population
144,668
Household Income
Household Income
Median Income
$52,004
Housing
Housing
Total Housing Units
65,702
Business & Economy
Business & Economy
Total Businesses
3,379
Employment
Employment
Employment Rate
54.55%
Education
Education
Bachelor's Degree+
23.93%
Source: U.S. Census ACS 2024 5-Year Estimates · rolled up across the 14 ZIPs in this county.
Data Last Updated: June 1, 2026
ZIP Codes:14 ZIP Codes (11 Standard, 3 PO Box, 0 Unique) [See All]
Area Codes:843 / 854
Timezone:Eastern (GMT -05:00)
Local Time:2:13:39 PM
Population:144,668 [See All]
FIPS:45041
CBSA:Florence, SC
Land Area:978 sq mi
Water Area:4 sq mi
Coordinates:34.0575, -79.7378
Quick Link:
https://www.zip-codes.com/county/sc-florence.asp
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South Carolina's #14 most populous county
144,668 residents across 14 ZIPs — #14 of 46 South Carolina counties.

Standout ZIPs in this County


Most Populous
Florence · 48,673 people
33.6% of county total
Highest Income
Florence · $71,671 median
1.4× county average
Largest Land Area
Lake City · 162.8 sq mi
Spans the most ground
Fastest Growth
Coward · 16.2% (10-yr)
2,273 → 2,641 residents
Most Educated
Florence · 33.5% bachelor's+
11,236 of 33,560 adults 25+

Things worth knowing about Florence County


144,668 residents live across 14 ZIPs covering 978 sq mi, served by 9 distinct USPS-recognized cities.

Population moved from 146,904 to 144,668 from 2014 to 2024 — a -1.5% change. 3 ZIPs gained residents, 8 lost.

The county's wealthiest ZIP 29501 (Florence, $71,671 median) and poorest ZIP 29583 (Pamplico, $34,931) are 22.6 miles apart — a 2.1× income gap across local geography.

Median home values vary 2.5× across this county — from $93,300 in 29591 (Scranton) to $236,900 in 29501 (Florence).

Density varies 21× across the county — from 44 people/sq mi in 29583 (Pamplico) to 922 in 29501 (Florence).

Educational attainment ranges from 7.7% bachelor's+ in 29530 (Coward) to 33.5% in 29501 (Florence) — the breadth of educational profiles across the area.

Within South Carolina, this is the #14 most populous of 46 counties and ranks #31 for median household income .

Weighted by population, the typical household earns about $58,288 across the county — reflecting what a typical resident sees, not a simple ZIP average.

23.9% of adults age 25+ hold a bachelor's degree or higher (23,575 of 98,498 reporting). The most-educated ZIPs cluster around Florence.

11 Standard delivery, 3 PO Box only, 0 single-entity Unique ZIPs serve this county.

All ZIP Codes in Florence County


ZIPCityTypePopulationMedian IncomeArea (sq mi)10-yr Growth
29501FlorenceStandard48,673$71,67152.88.9%
29505FlorenceStandard23,895$67,34350.5-8.4%
29506FlorenceStandard20,777$40,311137.0-2.7%
29560Lake CityStandard12,277$46,601162.8-4.8%
29161TimmonsvilleStandard9,688$50,517135.2-12.7%
29541EffinghamStandard9,326$52,06780.0-5.4%
29555JohnsonvilleStandard5,972$43,011103.26.7%
29583PamplicoStandard4,994$34,931112.6-10.8%
29591ScrantonStandard4,639$65,00055.1-10.1%
29530CowardStandard2,641$44,01254.616.2%
29114OlantaStandard1,786$56,57934.0-22.9%
29504FlorencePO Box0.0
29502FlorencePO Box0.0
29503FlorencePO Box0.0

Adjacent & Nearby Counties